ABSTRACT
Broiler leg diseases are a common abnormal bone metabolism issue that leads to poor leg health in growing poultry. Bone metabolism is a complicated regulatory process controlled by genetic, nutritional, feeding management, environmental, or other influencing factors. The gut microbiota constitutes the largest micro-ecosystem in animals and is closely related to many metabolic disorders, including bone disease, by affecting the absorption of nutrients and the barrier function of the gastrointestinal tract and regulating the immune system and even the brain-gut-bone axis. Recently, probiotic-based dietary supplementation has emerged as an emerging strategy to improve bone health in chickens by regulating bone metabolism based on the gut-bone axis. This review aims to summarize the regulatory mechanisms of probiotics in the gut microbiota on bone metabolism and to provide new insights for the prevention and treatment of bone diseases in broiler chickens.
ABSTRACT
The treatment of tumor has a strong timeliness and periodicity. Due to the duration of COVID-19 outbreak of is uncertain, patients with malignant tumors may have recurrent or progressive disease if they are not treated effectively for a long time. Several studies have shown that delayed chemotherapy and endocrine therapy may have adverse effects on the prognosis of cancer patients. Under the epidemic situation, it has become the key problem to be solved urgently by oncologists that how to better serve cancer patients, prevent and control the infection of cancer patients and their families, how to adjust and optimize the hospital treatment process, so as to ensure the scientific and orderly development of clinical work, and minimize the impact of the epidemic on the treatment of cancer patients. This paper focuses on effectively guiding the emergency management, diagnosis and treatment process, reasonable follow-up, scientific epidemic prevention, reducing the risk of transmission and paying close attention to the mental health of tumor patients, to provide the reference for improving the prognosis of tumor patients during the epidemic situation.